Sulfosuccinimidyl oleate sodium is neuroprotective and alleviates stroke-induced neuroinflammation.

Hiramani DhunganaMikko T HuuskonenMerja JaronenSighild LemarchantHumair AliVelta Keksa-GoldsteineGundars GoldsteinsKatja M KanninenJari KoistinahoTarja Malm

Published in: Journal of neuroinflammation (2017)

Our results suggest that SSO is an anti-inflammatory and a possible therapeutic candidate in diseases such as stroke where inflammation is a central hallmark.

Keyphrases

cerebral ischemia
atrial fibrillation
anti inflammatory
oxidative stress
high glucose
subarachnoid hemorrhage
traumatic brain injury
blood brain barrier
lipopolysaccharide induced
brain injury
cognitive impairment
mouse model
endothelial cells
stress induced