Maternal Nutrition Affects Nitrogen Isotopic Signature in Blood Plasma of Beef Cattle Dams and Their Offspring.
Gabriela de Pauli MecianoFernando José Schalch JuniorGuilherme Henrique Gebim PolizelArícia Christofaro FernandesRoberta Cavalcante CraccoArlindo Saran NettoRodrigo da Costa GomesNara Regina Brandão CônsoloMiguel Henrique de Almeida SantanaPublished in: Metabolites (2022)
This study evaluated the effects of gestational supplementation strategy on nitrogen isotopic signature in blood plasma of beef cows and their progeny. The study comprised 15 pregnant Nellore cows divided into three different supplementation protocols: NP) non-programmed group; PP) cows receiving protein-energy supplement in the last third of pregnancy; and FP) cows receiving protein-energy supplement throughout the gestational period. Blood plasma from cows was sampled at the beginning of gestation, in the prepartum, and postpartum periods as well as from their calves at 30 and 180 days of age, for the analysis of stable isotope ratios 15 N/14 N. At pre- and postpartum periods, cows fed PP and FP presented greater abundance of δ15 N compared to NP ( p < 0.05) at pre- and postpartum. All three groups showed significant differences ( p < 0.05) in the postpartum period. The δ15 N values of calves at 30 days of age differed between the NP group and PP and FP groups ( p < 0.05), with no difference ( p > 0.05) at 180 days of age. The different gestational supplementation strategies influenced isotopic fractionation of nutrients of cows and their calves after birth, indicating effects on nutritional metabolism and cumulative behavior on isotope abundance related to consumption during gestation.
Keyphrases
- pregnancy outcomes
- pregnant women
- weight gain
- birth weight
- gestational age
- preterm infants
- physical activity
- body mass index
- type diabetes
- preterm birth
- high fat diet
- adipose tissue
- metabolic syndrome
- high resolution
- risk assessment
- mass spectrometry
- amino acid
- skeletal muscle
- insulin resistance
- small molecule
- drug induced