Multiple functions of the scaffold protein Discs large 5 in the control of growth, cell polarity and cell adhesion in Drosophila melanogaster.

Parvathy VenugopalHugo VeyssièreJean-Louis CoudercGraziella RichardCaroline VachiasVincent Mirouse

Published in: BMC developmental biology (2020)

Together our data show that Dlg5 own several conserved functions that are independent of each other in regulating growth, cell polarity and cell adhesion. Moreover, they reveal a differential regulation of E-cadherin and N-cadherin apical localization.

Keyphrases

cell adhesion
single cell
drosophila melanogaster
cell therapy
stem cells
gene expression
machine learning
electronic health record
mesenchymal stem cells
binding protein
big data