The microRNA-204-5p inhibits APJ signalling and confers resistance to cardiac hypertrophy and dysfunction.

Ravinder Reddy GaddamYoung-Rae KimJulia S JacobsJin-Young YoonQiuxia LiAngela CaiHamsitha ShankaiahgariBarry LondonKaikobad IraniAjit Vikram

Published in: Clinical and translational medicine (2022)

Our results show that miR-204 regulates trafficking of APJ and confers resistance to pressure overload-induced CH/CD, and boosting miR-204 can inhibit the development of CH/CD.

Keyphrases

cell proliferation
long non coding rna
long noncoding rna
room temperature
high glucose
nk cells
oxidative stress
diabetic rats
drug induced
endothelial cells