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Foreskin-derived mesenchymal stromal cells with aldehyde dehydrogenase activity: isolation and gene profiling.

Mehdi NajarEmerence CrompotLeo A van GrunsvenLaurent DolléLaurence Lagneaux
Published in: BMC cell biology (2018)
Taken together, this preliminary study suggests that distinct subsets of FSK-MSCs with differential gene expression profiles depending of ALDH activity could be identified. These populations could differ in terms of biological functionalities involving the selection by ALDH activity as useful tool for potent therapeutic applications. However, functional studies should be conducted to confirm their therapeutic relevance.
Keyphrases
  • genome wide
  • copy number
  • bone marrow
  • gene expression
  • dna methylation