Effects of medications on incidence and risk of knee and hip joint replacement in patients with osteoarthritis: a systematic review and meta-analysis.

Beibei CuiYuehong ChenYunru TianHuan LiuYupeng HuangGeng YinQibing Xie

Published in: Advances in rheumatology (London, England) (2022)

Bisphosphonate treatment is associated with a reduced risk of knee replacement. More studies are needed to validate our results due to the limited number of eligible studies and high heterogeneity among studies.

Keyphrases

total knee arthroplasty
knee osteoarthritis
case control
risk factors
replacement therapy