Supplemental Vitamin D and Incident Fractures in Midlife and Older Adults.
Meryl S LeBoffSharon H ChouKristin A RatliffNancy R CookBharti KhuranaEunjung KimPeggy M CawthonDouglas C BauerDennis BlackJ Chris GallagherI-Min LeeJulie E BuringJoAnn E MansonPublished in: The New England journal of medicine (2022)
supplementation did not result in a significantly lower risk of fractures than placebo among generally healthy midlife and older adults who were not selected for vitamin D deficiency, low bone mass, or osteoporosis. (Funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases; VITAL ClinicalTrials.gov number, NCT01704859.).