Lycium barbarum polysaccharide-glycoprotein promotes osteogenesis in hPDLSCs via ERK activation.

Shuang LaiChang LiuCong LiuLiyuan FanXinlun LiYiling YangYushu ZhuLi DengLi XiaoYandong Mu

Published in: Oral diseases (2022)

LBP promoted hPDLSC osteogenesis by targeting the ERK1/2 signaling pathway and reverse bone loss by reducing inflammation. These findings provided latent hope for LBP application in periodontal therapy.

Keyphrases

signaling pathway
bone loss
pi k akt
induced apoptosis
epithelial mesenchymal transition
oxidative stress
cell proliferation
bone regeneration
bone marrow