Patients with Type 1 Diabetes Treated with Insulin Pumps Need Widely Heterogeneous Basal Rate Profiles Ranging from Negligible to Pronounced Diurnal Variability.

Anna M LindmeyerJuris J MeierMichael A Nauck

Published in: Journal of diabetes science and technology (2020)

We observe substantial interindividual heterogeneity in the "dawn" phenomenon. However, widely different empirically derived basal insulin infusion profiles appear appropriate for individual patients, as indicated by similar plasma glucose concentrations, mainly in the target range, during a 24-hour fasting period.

Keyphrases

type diabetes
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
blood pressure
prognostic factors
peritoneal dialysis
glycemic control
metabolic syndrome
patient reported outcomes
weight loss
skeletal muscle
adipose tissue