Frequency of azole resistance in clinical and environmental strains of Aspergillus fumigatus in Turkey: a multicentre study.

Beyza EnerÇağrı ErginDolunay GülmezHarun AğcaMelek TikveşliSeçil Ak AksoyMüşerref OtkunAli Korhan SiğDilara ÖğünçBetil ÖzhakTuncay TopaçAslı ÖzdemirDilek Yeşim MetinSüleyha Hilmioğlu PolatYasemin ÖzNedret KoçMustafa Altay AtalayZayre ErturanAsuman BirinciNilgün ÇerikçioğluDemet TimurFahriye EkşiGonca Erköse GençDuygu FindikŞaban GürcanAyşe KalkanciSevtap Arikan-Akdagli

Published in: The Journal of antimicrobial chemotherapy (2022)

The rate of observed azole resistance of A. fumigatus isolates was low in this study, but the fact that more than half of the examined strains had the wild-type cyp51A gene supports the idea that other mechanisms of resistance are gradually increasing.

Keyphrases

wild type
escherichia coli
candida albicans
genome wide
dna methylation
risk assessment
transcription factor
climate change
genome wide analysis