Neutral polysaccharide from Gastrodia elata alleviates cerebral ischemia-reperfusion injury by inhibiting ferroptosis-mediated neuroinflammation via the NRF2/HO-1 signaling pathway.
Yonggang ZhangPeng YeHua ZhuLijuan GuYuntao LiShi FengZhi ZengQian-Xue ChenBenhong ZhouXiao-Xing XiongPublished in: CNS neuroscience & therapeutics (2023)
Collectively, our results demonstrate the protective effects of NPGE and highlight its therapeutic potential as a drug component for CIRI treatment.