Prognostic significance of laterality in lung neuroendocrine tumors.
Anna La SalviaIrene PersanoAlessandra SicilianiMonica VerricoMassimiliano BassiRoberta ModicaAlessandro AudisioIsabella ZanataBeatrice Trabalza MarinucciElena TrevisiGiulia PulianiMaria RinzivilloElena ParlagrecoRoberto BaldelliTiziana FeolaFranz SestiPaola RazzoreRossella MazzilliMassimiliano ManciniFrancesco PanzutoMarco VolanteElisa GiannettaCarmen RomeroMarialuisa AppetecchiaAndrea IsidoriFederico VenutaMaria Rosaria AmbrosioMaria Chiara ZatelliMohsen IbrahimAnnamaria ColaoMaria Pia BrizziRocío García-CarboneroAntongiulio FaggianoPublished in: Endocrine (2022)
This study highlights that laterality is an independent prognostic factors in Lu-NETs, with left tumors being less frequent but showing a worse prognosis than right ones. A wider spectrum of clinical and pathological prognostic factors, including TNM stage, age and laterality is suggested. These parameters could help clinicians to personalize the management of Lu-NET.