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Establishment and characterization of a HER2-enriched canine mammary cancerous myoepithelial cell line.

Aolei ChenShaotang YeJiahui ZhengJichao LiZejia ChenYashan ZhangShoujun Li
Published in: BMC veterinary research (2023)
A canine cancerous HER2-enriched myoepithelial cell line was successfully established and a canine mammosphere developed from myoepithelial cells was documented in this study. We are expecting this novel cell line and its associated mammospheres could be used as a model to elucidate the role of myoepithelial cells in CMT carcinogensis in the future.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • endoplasmic reticulum stress
  • oxidative stress
  • signaling pathway
  • current status
  • cell proliferation