Establishment and characterization of a HER2-enriched canine mammary cancerous myoepithelial cell line.

Aolei ChenShaotang YeJiahui ZhengJichao LiZejia ChenYashan ZhangShoujun Li

Published in: BMC veterinary research (2023)

A canine cancerous HER2-enriched myoepithelial cell line was successfully established and a canine mammosphere developed from myoepithelial cells was documented in this study. We are expecting this novel cell line and its associated mammospheres could be used as a model to elucidate the role of myoepithelial cells in CMT carcinogensis in the future.

Keyphrases

induced apoptosis
cell cycle arrest
endoplasmic reticulum stress
oxidative stress
signaling pathway
current status
cell proliferation