Metabolomic Pathway Activity with Genomic Single-Nucleotide Polymorphisms Associated with Colorectal Cancer Recurrence and 5-Year Overall Survival.
Christina A FlemingHelen M MohanDonal P O'LearyMark CorriganH Paul RedmondPublished in: Journal of gastrointestinal cancer (2022)
With a caveat on study heterogeneity, specific metabolites and metabolic pathway activity appear evident in the setting of poor prognostic colorectal cancers and such metabolic signatures are associated with specific genomic SNPs.