Bronchiolitis and recurrent wheezing are distinguished by type 2 innate lymphoid cells and immune response.
Beatriz SastreMaría Luz García-GarcíaJosé Antonio CañasChristina CalvoJosé Manuel Rodrigo-MuñozInmaculada CasasIgnacio Mahillo FernándezVictoria Del PozoPublished in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (2020)
Bronchiolitis is associated with elevated nasal percentage of ILC2. This cellular population could be the key element in the differential immune response between BCH and RW which share some mechanisms such us monocyte activation, vascular damage, and fibroblast repair. Lipid mediators could play a role in the evolution of the disease later in life through innate lymphoid cells.