SEOM-GEINO clinical guidelines for grade 2 gliomas (2023).
María Angeles Vaz SalgadoBelén Cigarral GarcíaIsaura Fernández PérezBeatriz Jiménez MunárrizPaula Sampedro DomarcoAinhoa Hernández GonzálezMaría Vieito VillarRaquel Luque CaroMaría Luisa Villamayor DelgadoJuan Manuel Sepúlveda SánchezPublished in: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico (2024)
The 2021 World Health Organization (WHO) classification has updated the definition of grade 2 gliomas and the presence of isocitrate dehydrogenase (IDH) mutation has been deemed the cornerstone of diagnosis. Though slow-growing and having a low proliferative index, grade 2 gliomas are incurable by surgery and complementary treatments are vital to improving prognosis. This guideline provides recommendations on the multidisciplinary treatment of grade 2 astrocytomas and oligodendrogliomas based on the best evidence available.