Loss of Response to Anti-Tumor Necrosis Factor Alpha Therapy in Crohn's Disease Is Not Associated with Emergence of Novel Inflammatory Pathways.
Jay LutherManish GalaSuraj J PatelManeesh DaveNynke BorrenRamnik J XavierAshwin N AnanthakrishnanPublished in: Digestive diseases and sciences (2018)
Our analyses suggest that loss of response to anti-TNFα is not driven by the emergence of pathways that bypass the action or induce resistance to anti-TNFα therapy.