Sustained remission following the discontinuation of tofacitinib in patients with rheumatoid arthritis (XANADU study): an open-label randomised study.
Yasuyuki TodorokiYusuke MiyazakiKoichi AmanoKiyoshi MatsuiHideto KamedaYoshino InoueShingo NakayamadaTakehisa OguraYuko KanekoKunihiro YamaokaYoshiya TanakaPublished in: RMD open (2023)
This study implies that a blanket cessation of tofacitinib may not be suitable for all patients, given that 58% of the participants experienced relapse. However, the withdrawal of tofacitinib is unlikely to result in the acquisition of treatment-resistance.