IL-6 -572C>G and CARD8 304T>A Genetic Polymorphisms are Associated with the Absolute Neutrophil Count in Patients with Hematological Malignancies Under Chemotherapy: An Application of Multilevel Models to a Preliminary Pharmacogenetic Study.
Matias F MartinezEnzo AlvealTomas G SotoEva I BustamanteFernanda ÁvilaShrikant I BangdiwalaIvonne FloresClaudia BenavidesRicardo MoralesNelson M VarelaLuis Abel QuiñonesPublished in: Pharmacogenomics and personalized medicine (2020)
IL-6 rs1800796 -572C>G and CARD8 rs2043211 304T>A polymorphisms are associated with the absolute neutrophil count in patients undergoing cytotoxic chemotherapy for treatment of hematological malignancies. Our findings might be useful to improve the safety of chemotherapy through predictive ANC models.