Bushenhuoxue Formula Facilitates Articular Cartilage Repair and Attenuates Matrix Degradation by Activation of TGF-β Signaling Pathway.
Rui DongJun YingTaotao XuSongfeng HuPeng ZhangChenjie XiaLiang FangHongting JinPinger WangPublished in: Evidence-based complementary and alternative medicine : eCAM (2018)
By activation of TGF-β signaling, BSHX formula can promote articular cartilage repair by accelerating chondrocyte proliferation and maintaining chondrocyte phenotype, upregulate ECM accumulation, and inhibit matrix degradation.