Evidence of artemisinin partial resistance in North-western Tanzania: clinical and drug resistance markers study.
Deus S IshengomaCeline I MandaraCatherine BakariAbebe A FolaRashid A MadebeMisago D SethFilbert FrancisCreyton BuguziRamadhan MoshiIssa GarimoSamwel LazaroAbdallah LusasiSijenunu AaronFrank ChackyAlly MohamedRitha J A NjauJovin KitauCharlotte RasmussenJeffrey A BaileyJonathan J JulianoMarian WarsamePublished in: medRxiv : the preprint server for health sciences (2024)
These findings confirm the presence of ART-R in Tanzania. A context-specific strategy to respond to artemisinin partial resistance is urgently needed. Although both AL and ASAQ showed high efficacy, increased vigilance for reduced efficacy of these ACTs and detection of ART-R in other parts of the country is critical.