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Oleuropein-driven reprogramming of the myeloid cell compartment to sensitise tumours to PD-1/PD-L1 blockade strategies.

Ester BlancoNoelia Silva-PilipichAna Isabel BocanegraLuisa ChocarroAntonio ProcopioKarina AusínJoaquín Fernandez-IrigoyenLeticia FernándezNerea RazquinAna IgeaMaider GarnicaMiriam EchaideHugo ArasanzRuth VeraDavid EscorsCristian SmerdouGrazyna Kochan
Published in: British journal of cancer (2024)
Oleuropein significantly improves the outcome of PD-1/PD-L1 blockade immunotherapy strategies by reprogramming myeloid cells.
Keyphrases
  • induced apoptosis
  • dendritic cells
  • bone marrow
  • acute myeloid leukemia
  • cell cycle arrest
  • single cell
  • cell therapy
  • endoplasmic reticulum stress
  • stem cells
  • cell death
  • oxidative stress
  • signaling pathway