IFIT1 modulates the proliferation, migration and invasion of pancreatic cancer cells via Wnt/β-catenin signaling.

Tian-Hao LiBang-Bo ZhaoCheng QinYuan-Yang WangZe-Ru LiHong-Tao CaoXiao-Ying YangXing-Tong ZhouWei-Bin Wang

Published in: Cellular oncology (Dordrecht) (2021)

Our data indicate that IFIT1 increases pancreatic cancer cell proliferation, migration and invasion by activating the Wnt/β-catenin pathway. In addition, we found that EMT could be regulated by IFIT1. IFIT1 may serve as a potential therapeutic target for pancreatic cancer.

Keyphrases

cell proliferation
signaling pathway
stem cells
cell cycle
epithelial mesenchymal transition
electronic health record
pi k akt
big data
risk assessment
data analysis