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Pharmacokinetics of 2 oral paracetamol formulations in hospitalized octogenarians.

Julie HiasLorenz Van der LindenKarolien WalgraeveMatthias GijsenPaola MianBirgit C P KochKarel AllegaertPieter AnnaertJos TournoyIsabel Spriet
Published in: British journal of clinical pharmacology (2021)
Large interindividual differences were found for pharmacokinetic parameters of oral paracetamol in frail inpatients after multiple dosing. Female sex and higher total serum bilirubin concentrations were associated with paracetamol exposure. No significant differences were observed between the tablet and granulate.
Keyphrases
  • anti inflammatory drugs