Sirolimus and propranolol inhibit endothelial proliferation while detergent sclerosants induce endothelial activation, microparticle release and apoptosis in vitro.
David Ewan ConnorJessica GerbelliAn-Ning ChewOsvaldo Cooley-AndradeDulani GoonawardhanaKelvin CheungKurosh ParsiPublished in: Phlebology (2020)
Sublytic concentrations of detergent sclerosants induce endothelial activation and the release of endothelial microparticles. All agents were anti-proliferative in EOMA cell lines, with sodium tetradecyl sulphate and polidocanol inducing cellular apoptosis.