Antibodies to biotinylated red blood cells in adults and infants: improved detection, partial characterization, and dependence on red blood cell-biotin dose.
Robert L SchmidtDonald M MockRobert S FrancoRobert M CohenAnne K NorthJosé A CancelasChristof GeisenRonald G StraussAlexander P VlaarDemet NalbantJohn A WidnessPublished in: Transfusion (2017)
The gel card assay is more sensitive than the tube agglutination assay. We recommend reagent BioRBC-256 for identifying anti-BioRBCs. Use of a low total RBC biotin label dose (≤ BioRBC-18) may minimize antibody induction.