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Antibodies to biotinylated red blood cells in adults and infants: improved detection, partial characterization, and dependence on red blood cell-biotin dose.

Robert L SchmidtDonald M MockRobert S FrancoRobert M CohenAnne K NorthJosé A CancelasChristof GeisenRonald G StraussAlexander P VlaarDemet NalbantJohn A Widness
Published in: Transfusion (2017)
The gel card assay is more sensitive than the tube agglutination assay. We recommend reagent BioRBC-256 for identifying anti-BioRBCs. Use of a low total RBC biotin label dose (≤ BioRBC-18) may minimize antibody induction.
Keyphrases
  • red blood cell
  • high throughput
  • loop mediated isothermal amplification
  • label free
  • wound healing