Anti-TNFα therapy in IBD alters brain activity reflecting visceral sensory function and cognitive-affective biases.

Marcus A GrayChe-Yung ChaoHeidi M StaudacherNatasha A KoloskyNicholas J TalleyGerald Holtmann

Published in: PloS one (2018)

In patients with Crohn's disease, anti-TNFα administration reduces visceral sensitivity and improves implicit cognitive-affective biases linked to alterations in limbic (amygdala) function.

Keyphrases

rheumatoid arthritis
bipolar disorder
insulin resistance
functional connectivity
resting state
prefrontal cortex
temporal lobe epilepsy