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Beyond large-effect loci: large-scale GWAS reveals a mixed large-effect and polygenic architecture for age at maturity of Atlantic salmon.

Marion Sinclair-WatersJørgen ØdegårdSven Arild KorsvollThomas MoenSigbjørn LienCraig R PrimmerNicola J Barson
Published in: Genetics, selection, evolution : GSE (2020)
These results reveal a mixed architecture of large-effect loci and a polygenic component that consists of multiple smaller-effect loci, suggesting a more complex genetic architecture of Atlantic salmon age at maturity than previously thought. This more complex architecture will have implications for selection on this key trait in aquaculture and for management of wild salmon populations.
Keyphrases
  • genome wide
  • dna methylation
  • gene expression
  • genome wide association study