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Vascular Endothelial Growth Factor A (VEGF-A) and Vascular Endothelial Growth Factor Receptor 2 (VEGFR-2) as Potential Biomarkers for Oral Squamous Cell Carcinoma: A Sri Lankan Study.

Sajith Tilal EdirisingheManjula Manoji WeerasekeraDulmini Kavindya De SilvaMovini Thisara DevminiShanaka PathmaperumaGayan Kanchana WijesingheThilini NisansalaAnuradha MaddumageHaizal Mohd HussainiAlison M RichHarsha De SilvaMilne TrudyRenuka GoonasingheKanishka De SilvaSurangi Yasawardena
Published in: Asian Pacific journal of cancer prevention : APJCP (2023)
VEGF-A gene expression, serum levels, and tissue VEGFR-2 levels correlated linearly with the stage and grade of the tumor. This study justifies the value of VEGF-A as a potential biomarker in OSCC in early detection of OSCC. More studies are needed to accept the use of VEGF-A.
Keyphrases
  • vascular endothelial growth factor
  • endothelial cells
  • gene expression
  • dna methylation