Pathological and immunological evaluation of different regimens of praziquantel treatment in a mouse model of Schistosoma mansoni infection.
Ulrich Membe FemoeHermine Boukeng JatsaValentin GreigertJulie BrunetCatherine CannetMérimé Christian KenfackNestor Gipwe FeussomJoseph Bertin Kadji FassiEmilenne Tienga NkondoAhmed Abou-BacarAlexander Wilhelm PfaffThéophile DimoPierre KamtchouingLouis-Albert Tchuem TchuentéPublished in: PLoS neglected tropical diseases (2022)
This study revealed that the administration of PZQ at 18 mg/kg/day for 28 consecutive days was the optimal effective posology for treating S. mansoni infection at the initial stage in a murine model.
Keyphrases