Identifying Active Substances and the Pharmacological Mechanism of Houttuynia cordata Thunb. in Treating Radiation-Induced Lung Injury Based on Network Pharmacology and Molecular Docking Verification.
Gui-Hua LaiFei WangDuo-Rui NieShu-Jun LeiZhuo-Jun WuJian-Xiong CaoPublished in: Evidence-based complementary and alternative medicine : eCAM (2022)
Thunb. have a potential pharmacological effect against RILI via the cancer pathways, TNF signaling pathway, and PI3K-Akt signaling pathway.
Keyphrases
- pi k akt
- molecular docking
- radiation induced
- signaling pathway
- cell cycle arrest
- radiation therapy
- cell proliferation
- molecular dynamics simulations
- papillary thyroid
- epithelial mesenchymal transition
- induced apoptosis
- rheumatoid arthritis
- squamous cell
- drinking water
- squamous cell carcinoma
- young adults
- oxidative stress
- risk assessment
- endoplasmic reticulum stress
- climate change