Additional value of advanced ultrasonography in pregnancies with two inconclusive cell-free DNA draws.

Francesca BardiBo B BetEva PajkrtIngeborg H LinskensMireille N BekkerErik A SistermansCaterina M BilardoAyten Elvan-Taşpınar

Published in: Prenatal diagnosis (2022)

In pregnancies with twice inconclusive NIPT due to low FF, fetal structural anomalies are not more prevalent than in the general obstetric population. The detailed anatomical assessment has the added value to detect phenotypical features suggestive of chromosomal/genetic aberrations and identify pregnancies where advanced genetic testing may be indicated.

Keyphrases

preterm birth
gestational age
copy number
pregnancy outcomes
pregnant women
magnetic resonance imaging
genome wide
gene expression
computed tomography