Tissue factor expressed by circulating cancer cell-derived microparticles drastically increases the incidence of deep vein thrombosis in mice.
Grace M ThomasA BrillS MezouarL CrescenceM GallantC DuboisD D WagnerPublished in: Journal of thrombosis and haemostasis : JTH (2015)
TF expressed on tumor MPs contributes to the increased incidence of cancer-associated venous thrombosis in mice in vivo. These MPs may adhere to NETs formed at the site of thrombosis.