The Relationship between Diurnal Measures of Tonic Alertness and Self-Reported Fatigue in Persons with Multiple Sclerosis-A Retrospective Data Analysis.

Jonas O WeinrichJochen Saliger Mareike EschweilerHans KarbeElke Kalbe Jörn Nielsen

Published in: Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists (2023)

These results show a relationship between subjective fatigue and tonic alertness. However, other variables also contribute to this association, suggesting that the RT differences between twice-daily measures of tonic alertness is not related to increased subjective fatigue in a substantial number of pwMS, which diminishes the diagnostic value. Further studies including relevant variables such as sleepiness are urgently needed.

Keyphrases

sleep quality
data analysis
multiple sclerosis
physical activity
depressive symptoms
obstructive sleep apnea