Intravenous acetaminophen (at 15 mg/kg/dose every 6 hours) in critically ill preterm neonates with patent ductus arteriosus: A prospective study.

Kannan SridharanMuna Al JufairiEman Al AnsariReem Al MarzooqZakariya HubailSadeq Jaafar Radhi HasanAbdulraoof Al Madhoob

Published in: Journal of clinical pharmacy and therapeutics (2021)

Intravenous acetaminophen at 15 mg/kg/dose every 6 hours was efficacious in 78.2% of the preterm neonates with PDA. We observed a lower incidence of hepatotoxicity, and AKI in the study population. No association was observed between the serum acetaminophen concentrations and PDA closure.

Keyphrases

low birth weight
liver injury
drug induced
preterm infants
preterm birth
high dose
acute kidney injury
gestational age
risk factors