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Rapid decline in ejection fraction and persistent elevation of troponin associated with cardiac amyloidosis.

Temidayo A AbeEric Y ChangGabrielle De AllieTaiwo AjoseChukwuemeka NwokikeNicolas Bakinde
Published in: SAGE open medical case reports (2020)
Cardiac amyloidosis is an increasingly recognized cause of heart failure. It remains underdiagnosed despite a significant morbidity and mortality rate. The mean survival in patients with cardiac amyloidosis is less than 1 year in untreated primary light-chain amyloidosis and less than 4 years in wild-type transthyretin amyloidosis. We report a unique case of a 78-year-old male with transthyretin cardiac amyloidosis, who presented with persistently elevated troponin and progressive heart failure unresponsive to conventional therapy. With this case, we would like to highlight the role of cardiac biomarkers in the early diagnosis of cardiac amyloidosis.
Keyphrases
  • left ventricular
  • heart failure
  • multiple myeloma
  • wild type
  • ejection fraction
  • stem cells
  • mesenchymal stem cells
  • bone marrow
  • cell therapy
  • transcatheter aortic valve replacement
  • acute heart failure