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A Comprehensive Comparison of Early-Onset and Average-Onset Colorectal Cancers.

Andrea CercekWalid K ChatilaRona YaegerHenry WalchGustavo Dos Santos FernandesAsha KrishnanLerie PalmairaAnna MaioYelena M KemelPreethi SrinivasanChaitanya BandlamudiErin Salo-MullenPrince R TejadaKimeisha BelanfantiJesse GalleJoseph VijaiNeil SegalAnna VargheseDiane L ReidyJinru ShiaEfsevia VakianiSebastian MondacaRobin MendelsohnMelissa A LumishFelix SteinrueckeNancy KemenyLouise ConnellKaruna GaneshArnold MarkowitzGarrett NashJose GuillemJ Joshua SmithPhillip B PatyLiying ZhangDiana L MandelkerOzge BirsoyMark E RobsonKenneth OffitBarry TaylorMichael BergerDavid SolitMartin WeiserLeonard B SaltzJulio Garcia AguilarNikolaus SchultzLuis A DiazZsofia K Stadler
Published in: Journal of the National Cancer Institute (2021)
EO-CRCs are more commonly left-sided and present with rectal bleeding and abdominal pain but are otherwise clinically and genomically indistinguishable from AO-CRCs. Aggressive treatment regimens based solely on the age at CRC diagnosis are not warranted.
Keyphrases
  • early onset
  • abdominal pain
  • late onset
  • atrial fibrillation
  • young adults
  • smoking cessation
  • clinical evaluation