Correlation of chemokines and growth factors with radiation-induced liver injury after interstitial high dose rate (HDR) brachytherapy of liver metastases.

Robert DammMaciej PechPaola CavalliFlorian HaagSeverin GylstorffJazan OmariMaximilian ThormannRicarda SeidenstickerJens RickeMax SeidenstickerBorna Relja

Published in: Journal of cancer research and clinical oncology (2022)

Tumor volume and threshold dose of irradiation damage correlated positively with MCP-1 and VEGF as well as NGF and CX3CL, respectively. Thus, investigation of biological mediators in blood samples from tumor patients may provide an appropriate tool to predict fRILI after interstitial HDR brachytherapy of liver metastases.

Keyphrases

liver metastases
high dose
stem cell transplantation
low dose
end stage renal disease
radiation therapy
ejection fraction
newly diagnosed
peritoneal dialysis
endothelial cells
prognostic factors
oxidative stress
vascular endothelial growth factor
squamous cell carcinoma
patient reported outcomes