The serum metabolome mediates the concert of diet, exercise, and neurogenesis, determining the risk for cognitive decline and dementia.
Andrea Du PreezSophie Lefèvre-ArbogastVikki HoughtonChiara de LuciaDorrain Y LowCatherine HelmerCatherine FéartCécile DelcourtCécile Proust-LimaMercè PallàsSilvie R RuigrokBarbara AltendorferRaúl González-DomínguezAlex Sánchez-PlaMireia Urpi-SardàCristina Andres-LacuevaLudwig AignerPaul J LucassenAniko KorosiClaudine ManachCécilia SamieriSandrine ThuretPublished in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2021)
Diet and exercise might influence neurogenesis long before the onset of CD and dementia. Alterations in HN could signify the start of the pathological process and potentially represent biomarkers for CD and dementia.