Evaluating causal associations of chronotype with pregnancy and perinatal outcomes and its interactions with insomnia and sleep duration: a Mendelian randomization study.

Qian YangMaria C MagnusFanny KilpiGillian SantorelliAna Luiza Gonçalves SoaresJane WestPer MagnusSiri E HåbergKate TillingDeborah A LawlorM Carolina BorgesEleanor C M Sanderson

Published in: medRxiv : the preprint server for health sciences (2023)

The suggestive interaction between insomnia and evening preference on preterm birth, if replicated, supports targeting insomnia prevention in women of reproductive age with an evening chronotype.

Keyphrases

preterm birth
sleep quality
low birth weight
gestational age
pregnancy outcomes
pregnant women
polycystic ovary syndrome
cancer therapy
adipose tissue
depressive symptoms
metabolic syndrome