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Protein arginine methyltransferase 3 promotes glycolysis and hepatocellular carcinoma growth by enhancing arginine methylation of lactate dehydrogenase A.

Yu LeiPing HanYu ChenHan WangShuhui WangMuru WangJingmei LiuWei YanDean TianMei Liu
Published in: Clinical and translational medicine (2022)
Our results suggested a novel oncogenic role of PRMT3 in HCC, and it could be a promising therapeutic target for HCC by linking post-translational modification and cancer metabolism.
Keyphrases
  • nitric oxide
  • amino acid
  • papillary thyroid
  • squamous cell
  • dna methylation
  • transcription factor
  • genome wide
  • protein protein
  • lymph node metastasis
  • binding protein
  • gene expression
  • small molecule
  • young adults