Inhibition of CXXC5 function reverses obesity-related metabolic diseases.

Seol Hwa SeoEunhwan KimSoung-Hoon LeeYong-Ho LeeDai Hoon HanHyesun GoJe Kyung SeongKang-Yell Choi

Published in: Clinical and translational medicine (2022)

Overall, the inhibition of CXXC5 function by small molecule-mediated interference of Dvl binding is a potential therapeutic strategy for the treatment of obesity-related diabetes.

Keyphrases

small molecule
type diabetes
insulin resistance
metabolic syndrome
weight loss
weight gain
high fat diet induced
cardiovascular disease
glycemic control
adipose tissue
protein protein
physical activity
combination therapy
binding protein