Antiarrhythmic Mechanisms of Chinese Herbal Medicine Dingji Fumai Decoction.
Bo LiangYan ZhouLing FuHui-Ling LiaoPublished in: Evidence-based complementary and alternative medicine : eCAM (2020)
The clinical antiarrhythmic mechanisms of DFD are based on its antioxidant potential, alleviation of Na+-K+-ATPase and connexin-43, and class I antiarrhythmic properties by suppressing Nav1.5dose-dependently with an IC50 of 24.0 ± 2.4 mg/mL.