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DELEAT: gene essentiality prediction and deletion design for bacterial genome reduction.

Jimena SolanaEmilio Garrote-SánchezRosario Gil
Published in: BMC bioinformatics (2021)
Built on in silico gene essentiality predictions, we have developed an analysis pipeline which assists researchers throughout multiple stages of bacterial genome reduction projects, and created a novel classifier which is simple, fast, and universally applicable to any bacterial organism with a GenBank annotation file.
Keyphrases
  • genome wide
  • copy number
  • genome wide identification
  • molecular docking
  • quality improvement
  • rna seq
  • transcription factor
  • single cell