Quercetin enhances decidualization through AKT-ERK-p53 signaling and supports a role for senescence in endometriosis.
Julia DelenkoXiangying XueProdyot K ChatterjeeNathaniel HymanAndrew J ShihRobert P AdelsonPolona Safaric TepesPeter K GregersenChristine N MetzPublished in: Reproductive biology and endocrinology : RB&E (2024)
These data provide insight into the mechanisms of action of quercetin on endometrial stromal cells and warrant future clinical trials to test quercetin and other senolytics for treating endometriosis.