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Physiological significance of pre- and post-ejection left ventricular tissue velocities and relations to mitral and aortic valve closures.

Asbjørn StøylenAnnichen Søyland Daae
Published in: Clinical physiology and functional imaging (2021)
Electromechanical activation of the LV is simultaneous in septum and lateral wall, occurs before MVC, is terminated by MVC itself and is thus not isovolumic. Protodiastole is a short event of lengthening, predominantly in the septum. It may be the mechanism for valve closure and ends by AVC itself. Isovolumic relaxation occurs after this velocity spike, and is characterized by elongation of the apex, shortening of the base, thus showing a volume shift from base towards apex.
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