Greater daily glucose variability and lower time in range assessed with continuous glucose monitoring are associated with greater aortic stiffness: The Maastricht Study.
Yuri D ForemanWilliam P T M van DoornNicolaas C SchaperMarleen M J van GreevenbroekCarla J H van der KallenRonald M A HenryAnnemarie KosterSimone J P M EussenAnke WesseliusKoen D ReesinkMiranda T SchramPieter C DagnelieAbraham A KroonMartijn C G J BrouwersCoen D A StehouwerPublished in: Diabetologia (2021)
Our findings show that greater daily glucose variability and lower TIRCGM are associated with greater aortic stiffness (cf-PWV) but not with other arterial measures. If corroborated in prospective studies, these results support the development of therapeutic agents that target both daily glucose variability and TIRCGM to prevent CVD.