Removal of endothelial surface-associated von villebrand factor suppresses accelerate datherosclerosis after myocardial infarction.

Koya OzawaWilliam PackwoodMatthew A MullerYue QiAris XieOleg VarlamovOwen J McCartyDominic ChungJosé A LópezJonathan R Lindner

Published in: Journal of translational medicine (2024)

Plaque inflammatory activation in remote arteries after MI is strongly influenced by VWF-mediated platelet adhesion to the endothelium. These findings support investigation into new secondary preventive therapies for reducing non-culprit artery events after MI.

Keyphrases

nitric oxide
endothelial cells
signaling pathway
coronary artery disease
oxidative stress
biofilm formation
escherichia coli
cell migration
candida albicans