Effect of apolipoprotein E ε4 and its modification by sociodemographic characteristics on cognitive measures in South Asians from LASI-DAD.

Yi Zhe WangWei ZhaoPriya MoorjaniAlden L GrossXiang ZhouAparajit B DeyJinkook LeeJennifer A SmithSharon L R Kardia

Published in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2024)

APOE ε4 carriers had lower global and domain-specific cognitive performance. Females and older individuals may be more susceptible to ε4 effects. For most cognitive measures, there was no interaction between ε4 and education.

Keyphrases

healthcare
physical activity
cognitive decline
metabolic syndrome
middle aged
mass spectrometry
adipose tissue
high resolution
insulin resistance
liquid chromatography