Morphometric Analysis of Spina Bifida after Fetal Repair Shows New Subtypes with Associated Outcomes.
Lovepreet K MannShreya PandiriNeha AgarwalHope NorthrupKit Sing AuElin GrundbergEric P BerghMary T AustinRajan PatelBrandon MillerSen ZhuJonathan S FeinbergDejian LaiKuoJen TsaoStephen A FletcherRamesha PapannaPublished in: medRxiv : the preprint server for health sciences (2024)
There is a distinct phenotypic spectrum in open spina bifida with differential baseline presentation and outcomes. Severity of ventriculomegaly is associated with lesion type, rather than tonsillar herniation level. Our findings expand the classification of spina bifida to reveal a spectrum that warrants further study.